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Written by an international team of distinguished researchers and practitioners, the volume’s 49 chapters cover the relationship between microbial evolution and human biology from many perspectives. The first section illustrates the evolutionary biology of microbial-human interactions, considering the effect of human-driven changes. The second section analyzes evolutionary genetics involved in microbial variation and adaptation, from microbial genome to mobile elements as plasmids or integrons. The third section deals with evolutionary microbial responses to antibiotics, the major anthropogenic factor altering our interactions with microbes. Finally, the last three sections systematically analyze the evolution of pathogenesis in gram-negative and gram-positive bacteria, and fungi. These chapters convey the impact of evolution on microbe-human interactions, and how that influences infectious diseases. This information will stimulate an evolutionary orientation in the daily interpretation of facts that are observed in the laboratory and the hospital.

•  Provides many examples of the impact of evolution on microbe-human interactions and explores the influence that evolution has on infectious diseases
• Presents in-depth examination of the evolutionary biology of drug resistance
• Provides a useful, explanatory list of key words and concepts used in the field of evolutionary biology
• Features comprehensive coverage of the evolution of pathogenicity of gram-negative bacteria, gram-positive bacteria, and pathogenic fungi
• Provides significant new material for teaching microbiology and infectious diseases
• Offers contributions by internationally recognized experts in their respective fields

Hardcover, 668 pages, full-color insert, illustrations, index.