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This volume offers an up-to-date examination of the evolution of microbial pathogenesis, capitalizing on the explosion of knowledge in the field and the recent advent of microbial genome sequencing.  Written by experts in the field of microbial evolution and microbial pathogenesis, Evolution of Microbial Pathogens is a valuable reference for laboratory directors, postdoctoral fellows, and upper-level undergraduate and graduate students.

Composed of three main sections, the book provides comprehensive coverage with a dual focus on pathogenesis and methods used to study evolution.  The first section emphasizes broad themes of evolution and examines the process of studying evolution.  The second section provides examples of how problems that are common to various pathogens have been solved by evolution.  The remaining chapters cover a selection of well-studied classes of pathogens and the evolution of their disease-causing mechanisms.  Each section opens with an overview written by an investigator with broad expertise in the subject area, and individual chapters offer a list of key points to summarize the material covered.

Key Features

• Examines evolution of microbial pathogenesis, capitalizing on explosion of knowledge of molecular and genetic mechanisms and microbial genome sequencing
• Covers general concepts of microbial evolution including gene acquisition, gene loss, and the concept of microbial species
• Discusses the evolutionary forces generating beneficial and pathogenic relationships between microbes and hosts, and how these connections often overlap
• Considers evolution of pathogenic systems found in a variety of microbes or specific subsets of pathogens

Hardcover, 370 pages, illustrations, index.